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CAROLINA PANTHERS
SAN FRANCISCO 49ERS

Monday, November 24 8:15 PM ET
LATEST ODDS
The 49ers are heavy favorites to win at home against Carolina, in what is projected to be a 28.0 SF to 20.5 CAR game result.
LINE
SPREAD
O/U
+260
+7.5
48.5
-350
-7.5
48.5
ODDS OF WINNING
 CAR
SF 
74%
26%
IMPLIED TEAM TOTALS
Carolina
20.5 POINTS
28.0 POINTS
San Francisco
LAST 1 HEAD TO HEAD
San Francisco has won 1 of the last 1 games against Carolina.
DATE
SCORE
Oct 9, 2022
CAR 15 - SF 37
LAST 10 RESULTS
PANTHERS
49ERS
DATE
OPP
SCORE
Nov 9, 2025
vs  NO
L 7 - 17
Nov 2, 2025
@  GB
W 16 - 13
Oct 26, 2025
vs  BUF
L 9 - 40
Oct 19, 2025
@  NYJ
W 13 - 6
Oct 12, 2025
vs  DAL
W 30 - 27
Oct 5, 2025
vs  MIA
W 27 - 24
Sep 28, 2025
@  NE
L 13 - 42
Sep 21, 2025
vs  ATL
W 30 - 0
Sep 14, 2025
@  ARI
L 22 - 27
Sep 7, 2025
@  JAX
L 10 - 26
Nov 9, 2025
vs  LAR
L 26 - 42
Nov 2, 2025
@  NYG
W 34 - 24
Oct 26, 2025
@  HOU
L 15 - 26
Oct 19, 2025
vs  ATL
W 20 - 10
Oct 12, 2025
@  TB
L 19 - 30
Oct 2, 2025
@  LAR
W 26 - 23
Sep 28, 2025
vs  JAX
L 21 - 26
Sep 21, 2025
vs  ARI
W 16 - 15
Sep 14, 2025
@  NO
W 26 - 21
Sep 7, 2025
@  SEA
W 17 - 13
OFFENSIVE MATCHUP EDGE
AVERAGE SCORE
CAR
SF
Last 5 Games
15.0
22.8
Last 10 Games
17.7
22.0
This Season
17.7
22.0
DEFENSIVE MATCHUP EDGE
AVG SCORE ALLOWED
CAR
SF
Last 5 Games
20.6
26.4
Last 10 Games
22.2
23.0
This Season
22.2
23.0