ARIZONA CARDINALS vs
/ SAN FRANCISCO 49ERS

Sunday, November 16 4:05 PM ET · State Farm Stadium

State Farm Stadium

GAME STARTS IN

DAY

HOUR

MIN

SEC

LATEST ODDS

The 49ers are favorites to win against Arizona, in what is projected to be a 25.5 SF to 23.0 ARI game result.

MONEYLINE

SPREAD

O/U

ARIZONA ARI 3 - 5

+125

+2.5

48.5

SAN FRANCISCO SF 6 - 3

-150

-2.5

48.5

ODDS OF WINNING

ARI

SF

58%

43%

IMPLIED TEAM TOTALS

Arizona

23.0 POINTS

25.5 POINTS

San Francisco

LAST 6 HEAD TO HEAD

San Francisco has won 4 of the last 6 games against Arizona.

SEP 21, 2025

ARI 15 - SF 16

SPREAD

SF won against the spread

-1.5 SF

MONEYLINE

SF won straight up

-130 SF

TOTAL

The match went under 44.5 points

UNDER 44.5

JAN 5, 2025

ARI 47 - SF 24

SPREAD

ARI won against the spread

-4.5 ARI

MONEYLINE

ARI won straight up

-210 ARI

TOTAL

The match went over 42.5 points

OVER 42.5

OCT 6, 2024

ARI 24 - SF 23

SPREAD

ARI won against the spread

+7.5 ARI

MONEYLINE

ARI won straight up

+260 ARI

TOTAL

The match went under 49.5 points

UNDER 49.5

DEC 17, 2023

ARI 29 - SF 45

SPREAD

SF won against the spread

-12.5 SF

MONEYLINE

SF won straight up

-625 SF

TOTAL

The match went over 49.0 points

OVER 49.0

OCT 1, 2023

ARI 16 - SF 35

SPREAD

SF won against the spread

-14.0 SF

MONEYLINE

SF won straight up

-1000 SF

TOTAL

The match went over 43.5 points

OVER 43.5

JAN 8, 2023

ARI 13 - SF 38

SPREAD

Spread results are not available

N/A

MONEYLINE

M/L results are not available

N/A

TOTAL

Total results are not available

N/A

DATE

SCORE

MONEY

SPREAD

OVER/UNDER

WINNER

Sep 21, 2025

ARI 15 - SF 16

-130 SF

-1.5 SF

44.5 Under

WIN BY 1

Jan 5, 2025

ARI 47 - SF 24

-210 ARI

-4.5 ARI

42.5 Over

WIN BY 23

Oct 6, 2024

ARI 24 - SF 23

+260 ARI

+7.5 ARI

49.5 Under

WIN BY 1

Dec 17, 2023

ARI 29 - SF 45

-625 SF

-12.5 SF

49.0 Over

WIN BY 16

Oct 1, 2023

ARI 16 - SF 35

-1000 SF

-14.0 SF

43.5 Over

WIN BY 19

Jan 8, 2023

ARI 13 - SF 38

WIN BY 25

LAST 10 RESULTS

CARDINALS

49ERS

DATE

OPP

SCORE

MONEY

SPREAD

OVER/UNDERO/U

Nov 3, 2025

@

DAL

W 27 - 17

W +145

W +3.5

53.5 Under

Oct 19, 2025

vs

GB

L 23 - 27

L +300

L +6.5

44.5 Over

Oct 12, 2025

@

IND

L 27 - 31

L +260

L +7.5

46.5 Over

Oct 5, 2025

vs

TEN

L 21 - 22

L -450

L -7.5

41.5 Over

Sep 25, 2025

vs

SEA

L 20 - 23

L +110

L +1.5

43.5 Under

Sep 21, 2025

@

SF

L 15 - 16

L +110

L +1.5

44.5 Under

Sep 14, 2025

vs

CAR

W 27 - 22

W -325

L -6.5

45.5 Over

Sep 7, 2025

@

NO

W 20 - 13

W -290

W -6.5

43.5 Under

Jan 5, 2025

vs

SF

W 47 - 24

W -210

W -4.5

42.5 Over

Dec 28, 2024

@

LAR

L 9 - 13

L +250

L +6.5

47.5 Under

Nov 2, 2025

@

NYG

W 34 - 24

W -145

W -2.5

48.5 Over

Oct 26, 2025

@

HOU

L 15 - 26

L +110

L +2.5

42.5 Under

Oct 19, 2025

vs

ATL

W 20 - 10

W -110

W +0.5

46.5 Under

Oct 12, 2025

@

TB

L 19 - 30

L +150

L +3.5

47.5 Over

Oct 2, 2025

@

LAR

W 26 - 23

W +350

W +8.5

43.5 Over

Sep 28, 2025

vs

JAX

L 21 - 26

L -170

L -3.5

45.5 Over

Sep 21, 2025

vs

ARI

W 16 - 15

W -130

L -1.5

44.5 Under

Sep 14, 2025

@

NO

W 26 - 21

W -170

W -2.5

40.5 Over

Sep 7, 2025

@

SEA

W 17 - 13

W -130

W -1.5

43.5 Under

Jan 5, 2025

@

ARI

L 24 - 47

L +175

L +4.5

42.5 Over

OFFENSIVE MATCHUP EDGE

AVERAGE SCORE

ARI

SF

Last 5 Games

23.6

22.8

Last 10 Games

23.6

21.8

This Season

22.5

21.6

DEFENSIVE MATCHUP EDGE

AVG SCORE ALLOWED

ARI

SF

Last 5 Games

24.0

22.6

Last 10 Games

20.8

23.5

This Season

21.4

20.9